Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338067 | 1.00 | TSHR (0.35) | TSHRCYP2C19ALDH1A1 | |
| SCHEMBL10442825 | 1.00 | TSHR (0.35) | TSHRCYP2C19ALDH1A1 | |
| SCHEMBL30722274 | 0.92 | TSHR (0.41) | TSHRCYP2C19ALDH1A1 | |
| SCHEMBL16005200 | 0.79 | TSHR (0.32) | TSHRCYP2C19 | |
| SCHEMBL1745224 | 0.74 | — | — | |
| SCHEMBL9801526 | 0.74 | — | — | |
| SCHEMBL352244 | 0.72 | — | — | |
| SCHEMBL9802001 | 0.72 | TSHR (0.33) | TSHRCYP2C19ALDH1A1 | |
| SCHEMBL6228112 | 0.72 | — | — | |
| SCHEMBL10525010 | 0.69 | TSHR (0.31) | TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306605-B1 | ANTITUMOR PLATINUM COMPLEXES | Bristol-Myers Squibb Company (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0318464-B1 | ANTITUMOR PLATINUM COMPLEXES | Bristol-Myers Squibb Company (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0155705-B1 | ANTITUMOR PLATINUM COMPLEXES | Bristol-Myers Squibb Company (US) | 1989-12-13 | — | — | EP | disclosed |
| EP-0318464-A2 | Antitumor platinum complexes | Bristol-Myers Squibb Company (US) | 1989-05-31 | — | — | EP | disclosed |
| EP-0306605-A1 | Antitumor platinum complexes | Bristol-Myers Squibb Company (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4594418-A | A 1,2-cyclohexane platinum complex | BRISTOL-MYERS COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| US-4562275-A | ANTICARCINOGENIC AGENTS | BRISTOL-MYERS CO. (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0155705-A2 | Antitumor platinum complexes | Bristol-Myers Squibb Company (US) | 1985-09-25 | — | — | EP | disclosed |