Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752034 | 1.00 | GAA (0.38) | GAAL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL11363578 | 1.00 | GAA (0.38) | GAAL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL8127072 | 0.89 | GAA (0.38) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL3737134 | 0.89 | GAA (0.38) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL3737136 | 0.88 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2CA2 | |
| SCHEMBL10759442 | 0.87 | SMN1; SMN2 (0.33) | GAAMEN1KMT2AMMESMN1; SMN2 | |
| SCHEMBL10759449 | 0.87 | SMN1; SMN2 (0.33) | GAAMEN1KMT2AMMESMN1; SMN2 | |
| SCHEMBL9972674 | 0.86 | GAA (0.36) | GAAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL11388898 | 0.86 | GAA (0.36) | GAAL3MBTL1POLBMEN1KMT2A | |
| SCHEMBL11388894 | 0.86 | GAA (0.36) | GAAL3MBTL1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191989-B1 | ANTIBIOTIC ISOXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4897489-A | 2-/5-OXO-2-TETRAHYDROFURANY4-3-OXOISOXOL-IDINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4684641-A | BACTERICIDES | PFIZER INC. (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0168177-A2 | Cephalosporin antibiotics | Pfizer Limited (GB) | 1986-01-15 | — | — | EP | disclosed |