Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828075 | 0.89 | NOTUM (0.55) | NOTUMKDM4EMAPTOGG1TP53 | |
| SCHEMBL17771773 | 0.79 | NQO1 (0.39) | KDM4EMAPTTP53ALDH1A1TSHR | |
| SCHEMBL9687259 | 0.77 | NOTUM (0.64) | NOTUMALDH1A1XIAPBIRC2LMNA | |
| SCHEMBL13733355 | 0.76 | NOTUM (0.55) | NOTUMKDM4EALDH1A1XIAPBIRC2 | |
| SCHEMBL17446878 | 0.76 | NOTUM (0.62) | NOTUMXIAPBIRC2 | |
| SCHEMBL395606 | 0.76 | NOTUM (0.62) | NOTUMXIAPBIRC2 | |
| SCHEMBL31481108 | 0.76 | NOTUM (0.62) | NOTUMXIAPBIRC2 | |
| SCHEMBL31481087 | 0.76 | NOTUM (0.62) | NOTUMXIAPBIRC2 | |
| SCHEMBL17447342 | 0.74 | NOTUM (0.60) | NOTUMKDM4ETP53ALDH1A1HSD17B10 | |
| SCHEMBL1035499 | 0.73 | NOTUM (0.59) | NOTUMXIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511168-A1 | Indoline hydrochloride salts and process for their preparation | SANDOZ LTD. (CH) | 1992-10-28 | — | — | EP | disclosed |