⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622568 | 0.77 | TSHR (0.45) | — | |
| SCHEMBL7758078 | 0.74 | — | — | |
| SCHEMBL31312711 | 0.72 | — | — | |
| SCHEMBL6270090 | 0.72 | TSHR (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL7033333 | 0.69 | TSHR (0.53) | — | |
| SCHEMBL19688711 | 0.69 | — | — | |
| SCHEMBL23092979 | 0.69 | — | — | |
| SCHEMBL28622569 | 0.69 | EGLN1 (0.48) | — | |
| SCHEMBL38833 | 0.67 | — | — | |
| SCHEMBL29236883 | 0.67 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5085858-A | Thioglycolamide-functional siloxanes | DOW CORNING CORPORATION (US) | 1992-02-04 | — | — | US | disclosed |
| US-5068378-A | THIOGLYCOLAMIDE-FUNCTIONAL SILOXANES | DOW CORNING CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |
| US-4770873-A | OXIDIZING AGENT AND AN AMINO-FUNCTIONAL POLYMERIC SILICONE ADDITIVE | CLAIROL, INCORPORATED (US) | 1988-09-13 | — | — | US | disclosed |