Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392043 | 0.81 | HSD17B10 (0.45) | HSD17B10KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL7237335 | 0.81 | KDM4E (0.46) | PKMHSD17B10HDAC1HDAC8HDAC6 | |
| SCHEMBL13825839 | 0.81 | CLK4 (0.49) | HSD17B10TDP1HDAC1HDAC8KMT2A | |
| SCHEMBL1147662 | 0.81 | HSD17B10 (0.45) | HSD17B10HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL7599961 | 0.81 | SMN1; SMN2 (0.49) | HSD17B10HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL27428933 | 0.81 | MAPT (0.55) | HSD17B10HDAC8KMT2AMAPTL3MBTL1 | |
| SCHEMBL7058192 | 0.80 | HDAC8 (0.44) | HSD17B10HDAC1HDAC8HDAC6KMT2A | |
| SCHEMBL875144 | 0.80 | HSD17B10 (0.58) | HSD17B10TDP1KMT2AMAPTL3MBTL1 | |
| SCHEMBL22129311 | 0.79 | KDM4E (0.49) | PKMHSD17B10HDAC1HDAC8HDAC6 | |
| SCHEMBL11510637 | 0.78 | HDAC1 (0.59) | PKMHSD17B10MRGPRX4HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506709-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991008207-A1 | ARTHROPODICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |