Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690422 | 0.88 | ELANE (0.39) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL9432185 | 0.86 | ELANE (0.38) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL9690431 | 0.86 | ELANE (0.38) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL9548455 | 0.85 | ELANE (0.42) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL9689615 | 0.85 | ELANE (0.37) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL9432078 | 0.79 | ELANE (0.38) | ELANE | |
| SCHEMBL23258853 | 0.78 | ELANE (0.37) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL9431775 | 0.78 | ELANE (0.37) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL25601214 | 0.78 | ELANE (0.37) | ELANEMMP9MMP1CASP3KMT2A | |
| SCHEMBL9548487 | 0.77 | ELANE (0.44) | ELANEMMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481116-A1 | A process for producing halomethylcarbapenems | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-5064954-A | Phosphorylation of hydroxymethylcarbapem and halogenation; bactericides | SHIONOGI & CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |