Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.49 |
| ▸ | ACR | P10323 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689293 | 1.00 | PRSS1 (0.49) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9690343 | 0.89 | PRSS1 (0.50) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9690350 | 0.89 | PRSS1 (0.50) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27671251 | 0.85 | PRSS1 (0.62) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27690177 | 0.85 | PARP10 (0.50) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9689283 | 0.83 | PRSS1 (0.45) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9689279 | 0.83 | PRSS1 (0.45) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9690288 | 0.82 | PRSS1 (0.42) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9690295 | 0.82 | PRSS1 (0.42) | PRSS1ACRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27671252 | 0.81 | MAPT (0.58) | PRSS1ACRKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486702-A1 | PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-05-27 | — | — | EP | disclosed |