Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.79 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245092 | 0.89 | GAA (1.00) | GAANPC1RAB9ACYP1A2HSD17B10 | |
| SCHEMBL14207791 | 0.86 | GAA (0.74) | GAANPC1RAB9ACYP1A2HSD17B10 | |
| SCHEMBL2857964 | 0.84 | GAA (0.76) | GAANPC1RAB9ACYP1A2HSD17B10 | |
| SCHEMBL30071250 | 0.84 | GAA (0.76) | GAANPC1RAB9AHTTCYP1A2 | |
| SCHEMBL626827 | 0.84 | GAA (0.76) | GAANPC1RAB9AHTTCYP1A2 | |
| SCHEMBL12426307 | 0.84 | GAA (0.82) | GAANPC1RAB9ACYP1A2HSD17B10 | |
| SCHEMBL30444964 | 0.82 | HDAC3 (0.76) | GAANPC1RAB9AHTTCYP1A2 | |
| Bromide SCHEMBL11500766 | 0.82 | GAA (0.73) | GAANPC1RAB9AHTTCYP1A2 | |
| SCHEMBL8545451 | 0.82 | GAA (0.79) | GAANPC1RAB9ACYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL30225316 | 0.82 | GAA (0.73) | GAANPC1RAB9ACYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3992184-B1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEV CO LTD (CN) | 2024-05-29 | — | — | EP | disclosed |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| WO-2021216812-A1 | GALACTOKINASE INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021216812-A1 | GALACTOKINASE INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | disclosed |
| US-9751851-B2 | Molecules and compositions that inhibit gram negative bacteria and their uses | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| EP-0329357-B1 | DIHYDROPYRIDINE ANTI-ALLERGIC AND ANTI-INFLAMMATORY AGENTS | Pfizer Limited (GB) | 1992-07-15 | — | — | EP | disclosed |
| US-4904671-A | ANTIARTHRITIC AGENTS; PLATELET ACTIVATING FACTOR | PFIZER INC. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0330327-A2 | Dihydropyridines, their preparation and their use as PAF-antagonists | Pfizer Limited (GB) | 1989-08-30 | — | — | EP | disclosed |
| EP-0329357-A1 | Dihydropyridine anti-allergic and anti-inflammatory agents | Pfizer Limited (GB) | 1989-08-23 | — | — | EP | disclosed |
| US-4859686-A | Dihydropyridine anti-allergic and anti-inflammatory agents | PFIZER INC. (US) | 1989-08-22 | — | — | US | disclosed |
| US-4788205-A | ANTAGONISTS OF PLATELET ACTIVATING FACTOR | PFIZER INC. (US) | 1988-11-29 | — | — | US | disclosed |
| US-4491481-A | Organic pigment compositions containing an azo compound with a heterocyclic substituent | CIBA-GEIGY CORPORATION (US) | 1985-01-01 | — | — | US | disclosed |
| EP-0066226-A1 | Chromogenic development process for the formation of a magenta dye image, and colour photographic recording material suitable therefor | Agfa-Gevaert AG (DE) | 1982-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | GALK1, GCK, GCKR | GAA 101/4885NPC1 3021/4885RAB9A 2719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.