SCHEMBL9689442

SCHEMBL9689442

Cc1c(C(=O)c2ccccc2F)c2ccccc2n1CCN1CCOCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.77
CNR2 P34972 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9691166 0.88 CNR2 (0.78) CNR1CNR2
SCHEMBL10669175 0.87 CNR1 (1.00) CNR1CNR2
SCHEMBL9691335 0.86 CNR2 (0.63) CNR1CNR2
SCHEMBL9691346 0.86 CNR2 (0.63) CNR1CNR2
SCHEMBL9691330 0.86 CNR1 (0.58) CNR1CNR2
SCHEMBL9691439 0.85 CNR1 (0.77) CNR1CNR2
SCHEMBL10666370 0.85 CNR1 (0.79) CNR1CNR2
SCHEMBL9036925 0.85 CNR1 (0.77) CNR1CNR2
SCHEMBL9691491 0.85 CNR1 (0.74) CNR1CNR2
SCHEMBL10093007 0.84 CNR2 (0.77) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0171037-B1 3-CARBONYL-1-AMINOALKYL-1H-INDOLES USEFUL AS ANALGESICS AND PREPARATION THEREOF STERLING WINTHROP INC. (US) 1992-06-17 EP disclosed
US-5013732-A Analgesics STERLING DRUG INC. (US) 1991-05-07 US disclosed
US-4885295-A ANALGESICS; ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES STERLING DRUG INC. (US) 1989-12-05 US disclosed
US-4634776-A ANALGESIC, ANTIRHEUMATIC, ANTIINFLAMMATORY STERLING DRUG, INC. (US) 1987-01-06 US disclosed
US-4581354-A ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS STERLING DRUG INC. (US) 1986-04-08 US disclosed
EP-0171037-A2 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof STERLING WINTHROP INC. (US) 1986-02-12 EP disclosed