Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689573 | 1.00 | KMT2A (0.44) | KMT2AMAPTMEN1PRSS1ACR | |
| SCHEMBL9689279 | 0.92 | PRSS1 (0.45) | KMT2AMAPTMEN1PRSS1ACR | |
| SCHEMBL9689283 | 0.92 | PRSS1 (0.45) | KMT2AMAPTMEN1PRSS1ACR | |
| SCHEMBL9689734 | 0.83 | KMT2A (0.46) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL9689726 | 0.83 | KMT2A (0.46) | KMT2AMAPTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL9690350 | 0.83 | PRSS1 (0.50) | KMT2AMAPTMEN1PRSS1ACR | |
| SCHEMBL9690343 | 0.83 | PRSS1 (0.50) | KMT2AMAPTMEN1PRSS1ACR | |
| SCHEMBL9690288 | 0.83 | PRSS1 (0.42) | KMT2AMAPTMEN1PRSS1ACR | |
| SCHEMBL9690295 | 0.83 | PRSS1 (0.42) | KMT2AMAPTMEN1PRSS1ACR | |
| SCHEMBL27671252 | 0.83 | MAPT (0.58) | KMT2AMAPTMEN1PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486702-A1 | PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-05-27 | — | — | EP | disclosed |