⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688190 | 0.89 | — | — | |
| SCHEMBL9208043 | 0.88 | — | — | |
| SCHEMBL9689591 | 0.87 | CYSLTR2 (0.56) | — | |
| SCHEMBL9225368 | 0.86 | — | — | |
| SCHEMBL9284533 | 0.86 | — | — | |
| SCHEMBL9268470 | 0.83 | CYSLTR1 (0.63) | — | |
| SCHEMBL10590029 | 0.82 | — | — | |
| SCHEMBL9228653 | 0.81 | — | — | |
| SCHEMBL9200788 | 0.81 | — | — | |
| SCHEMBL9281256 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480716-A1 | Saturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |