Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | HMGCR | P04035 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 18/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951537 | 1.00 | ESR1 (0.49) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL6963451 | 0.91 | GCGR (0.52) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL6962770 | 0.83 | GCGR (0.65) | GCGR | |
| SCHEMBL9271666 | 0.82 | HMGCR (0.59) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL9271680 | 0.82 | HMGCR (0.59) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL7561153 | 0.82 | ESR1 (0.62) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL8973684 | 0.82 | ESR1 (0.62) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL7807309 | 0.82 | HMGCR (0.57) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL27362855 | 0.81 | HMGCR (0.67) | ESR1HMGCRCHRM1TBXA2RPDE4A | |
| SCHEMBL15329710 | 0.81 | ESR1 (0.48) | ESR1HMGCRCHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169857-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |
| US-5006530-A | Certain 7-[2,6-diisopropyl-4-phenyl-5-lower alkoxymethyl-pyrid-3-yl]-3,5-dihydroxy-6-enoates and derivatives useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |