Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13823398 | 0.81 | NOTUM (0.63) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL3373420 | 0.80 | NOTUM (0.53) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL19597426 | 0.77 | NOTUM (0.53) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL12920018 | 0.77 | NOTUM (0.53) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL16122138 | 0.77 | NOTUM (0.49) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL1059987 | 0.73 | MAPT (0.58) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL17470902 | 0.73 | NOTUM (0.45) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL17470901 | 0.73 | NOTUM (0.45) | NOTUMMAPTF2KCNJ1ALDH1A1 | |
| SCHEMBL15825886 | 0.72 | NOTUM (0.44) | NOTUMMAPTKCNJ1ALDH1A1LMNA | |
| Potassium Ion SCHEMBL14142028 | 0.72 | NOTUM (0.56) | NOTUMMAPTF2KCNJ1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156512-A1 | potent activity against resistant pneumococci | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NPM1 | NOTUM 3541/4885MAPT 3463/4885F2 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.