Sugi Predict

Sugi Predict / Compounds / SCHEMBL9690337

SCHEMBL9690337

SCHEMBL9690337

N=C(N)Nc1ccc(C(=O)Oc2ccc(OS(=O)(=O)/C=C/c3ccccc3)c(Cl)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 12/20 0.48
▸ NFE2L2 Q16236 4/20 0.38
▸ LMNA P02545 1/20 0.38
▸ KMT2A Q03164 3/20 0.37
▸ MEN1 O00255 2/20 0.37
▸ PRSS1 P07477 1/20 0.37
▸ PRSS2 P07478 1/20 0.37
▸ PRSS3 P35030 1/20 0.37
▸ FTO Q9C0B1 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9690347 1.00 PPARG (0.48) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9689802 0.93 PPARG (0.51) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9689814 0.93 PPARG (0.51) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9689846 0.87 PPARG (0.51) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9689855 0.87 PPARG (0.51) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9690542 0.86 PPARG (0.61) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9690534 0.86 PPARG (0.61) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9690467 0.86 PPARG (0.44) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9690456 0.86 PPARG (0.44) PPARGNFE2L2LMNAKMT2AMEN1
SCHEMBL9689301 0.86 PPARG (0.55) PPARGNFE2L2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0486702-A1 PHENYL 4-GUANIDINOBENZOATE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PROTEASE INHIBITOR CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-05-27 — — EP disclosed