SCHEMBL9690621

SCHEMBL9690621

CCCCCCOc1ccc2c(c1)CCN=C2C=Cc1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.56
THRA P10827 2/20 0.47
THRB P10828 2/20 0.47
AHR P35869 1/20 0.43
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
LSS P48449 1/20 0.41
MAOB P27338 5/20 0.41
MAOA P21397 3/20 0.41
ATP4A P20648 1/20 0.41
ATP4B P51164 1/20 0.41
PPARA Q07869 1/20 0.38
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9692826 1.00 SLC2A1 (0.56) SLC2A1THRATHRBAHRCA1
SCHEMBL9692415 0.97 SLC2A1 (0.59) SLC2A1THRATHRBAHRCA1
SCHEMBL9692407 0.97 SLC2A1 (0.59) SLC2A1THRATHRBAHRCA1
SCHEMBL9690752 0.92 SLC2A1 (0.65) SLC2A1THRATHRBAHRCA1
SCHEMBL9692583 0.92 SLC2A1 (0.65) SLC2A1THRATHRBAHRCA1
SCHEMBL9693001 0.89 SLC2A1 (0.58) SLC2A1THRATHRBAHRCA1
SCHEMBL9693003 0.89 SLC2A1 (0.58) SLC2A1THRATHRBAHRCA1
SCHEMBL9692816 0.87 SLC2A1 (0.43) SLC2A1THRATHRBAHRATP4A
SCHEMBL9692819 0.87 SLC2A1 (0.43) SLC2A1THRATHRBAHRATP4A
SCHEMBL9690487 0.87 SLC2A1 (0.60) SLC2A1THRATHRBAHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170524-B1 NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-07-15 EP claimed
EP-0170524-A2 Nitrogen containing heterocyclic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1986-02-05 EP claimed
EP-0170524-B1 NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-07-15 EP disclosed
US-4968698-A FUNGICIDES, ANTIPROTOZOA AGENTS BURROUGHS WELLCOME CO. (US) 1990-11-06 US disclosed
EP-0170524-A2 Nitrogen containing heterocyclic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1986-02-05 EP disclosed