SCHEMBL9690710

SCHEMBL9690710

O=C1c2cc(NCCC(c3ccccc3)c3ccccc3)ccc2S(=O)(=O)N1CSc1nnnn1-c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7410881 0.85 ELANE (0.65) ELANE
SCHEMBL7304289 0.82 ELANE (0.70) ELANE
SCHEMBL7301751 0.80 ELANE (0.80) ELANE
SCHEMBL7310549 0.80 ELANE (1.00) ELANE
SCHEMBL7304136 0.77 ELANE (0.73) ELANE
SCHEMBL7348006 0.76 ELANE (0.65) ELANE
SCHEMBL7412128 0.73 ELANE (0.80) ELANE
SCHEMBL8481489 0.72 ELANE (0.71) ELANE
SCHEMBL7416331 0.72 ELANE (1.00) ELANE
SCHEMBL7418531 0.71 ELANE (1.00) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471756-A4 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF 1992-04-08 EP disclosed
EP-0471756-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF. STERLING WINTHROP INC (US) 1992-02-26 EP disclosed