Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.68 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691328 | 1.00 | NR1I2 (0.68) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10776113 | 1.00 | NR1I2 (0.68) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10425319 | 0.94 | NR1I2 (0.66) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9679491 | 0.94 | NR1I2 (0.77) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL5439983 | 0.94 | NR1I2 (0.77) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL5439979 | 0.94 | NR1I2 (0.77) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL8631702 | 0.94 | NR1I2 (0.77) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11055144 | 0.94 | NR1I2 (0.77) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10847228 | 0.94 | NR1I2 (0.77) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL8628827 | 0.94 | NR1I2 (0.77) | NR1I2MAPTPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160252-B1 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1992-08-26 | — | — | EP | disclosed |
| EP-0164122-B1 | CEPHEM COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 1990-09-19 | — | — | EP | disclosed |
| EP-0164113-B1 | 3-PYRAZOLO(1,5-A)PYRIDINIUM CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4826834-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4788185-A | Cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0216385-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0164122-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0164113-A2 | 3-pyrazolo(1,5-a)pyridinium cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| EP-0160969-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-13 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |