Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61439 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL10933953 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL10932296 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL61125 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL6236479 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL10937742 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL60618 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL10975956 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL16604562 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 | |
| SCHEMBL61327 | 1.00 | HTT (0.60) | HTTDNM1KMT2AHSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188450-B1 | METHODS FOR THE IN VITRO DETECTION AND IDENTIFICATION OF UNKNOWN PATHOGENS OR GENETIC ENTITIES | DIAGNOSTIC RESEARCH LIMITED PARTNERSHIP (US) | 1992-08-12 | — | — | EP | claimed |