Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692712 | 1.00 | PIM1 (0.37) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9693682 | 1.00 | PIM1 (0.37) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694251 | 0.93 | PIM1 (0.43) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9692711 | 0.93 | PIM1 (0.43) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694206 | 0.93 | PIM1 (0.43) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9692687 | 0.90 | PIM1 (0.36) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694518 | 0.90 | PIM1 (0.36) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9692671 | 0.90 | PIM1 (0.36) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694412 | 0.89 | PIM1 (0.47) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694416 | 0.89 | PIM1 (0.47) | PIM1GSK3AGSK3BPIM3CSNK1G1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465716-A1 | Optically active thiazetoquino-line-3-carboxylic acid compound, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |