Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cyclohexanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27778416 | 0.97 | TSHR (0.67) | TSHRCES2CES1EPHX1ALDH1A1 | |
| Oxalic Acid SCHEMBL28391280 | 0.97 | TSHR (0.67) | TSHRCES2CES1EPHX1ALDH1A1 | |
| Cyclohexanol SCHEMBL30598077 | 0.90 | TSHR (0.67) | TSHRCES2CES1EPHX1ALDH1A1 | |
| Cyclohexanol SCHEMBL241715 | 0.90 | TSHR (0.67) | TSHRCES2CES1EPHX1ALDH1A1 | |
| Cyclopentanol SCHEMBL11102072 | 0.87 | TSHR (0.71) | TSHRCES2CES1EPHX1ALDH1A1 | |
| Cyclohexanol SCHEMBL9474284 | 0.87 | — | — | |
| Cyclohexanol SCHEMBL868909 | 0.85 | TSHR (0.59) | TSHRCES2CES1EPHX1ALDH1A1 | |
| Acetic Acid SCHEMBL6048336 | 0.85 | TSHR (0.59) | TSHRCES2CES1EPHX1ALDH1A1 | |
| Cyclohexanol SCHEMBL9019529 | 0.85 | TSHR (0.59) | TSHRCES2CES1EPHX1ALDH1A1 | |
| SCHEMBL23121456 | 0.83 | TSHR (0.91) | TSHRCES2CES1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171478-A | Doping with organic acids or salts; electroconductive | ALLIED-SIGNAL INC. (US) | 1992-12-15 | — | — | US | disclosed |