Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10397529 | 0.87 | PTAFR (0.82) | PTAFR | |
| Hydrochloric Acid SCHEMBL10397528 | 0.86 | PTAFR (0.76) | PTAFR | |
| SCHEMBL9694184 | 0.84 | PTAFR (1.00) | PTAFR | |
| Hydrochloric Acid SCHEMBL9691738 | 0.84 | PTAFR (0.71) | PTAFR | |
| SCHEMBL9691990 | 0.81 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9118339 | 0.81 | PTAFR (1.00) | PTAFR | |
| Hydrochloric Acid SCHEMBL10396468 | 0.80 | PTAFR (0.84) | PTAFR | |
| Hydrochloric Acid SCHEMBL9438229 | 0.80 | PTAFR (0.98) | PTAFR | |
| SCHEMBL9693616 | 0.79 | PTAFR (1.00) | PTAFR | |
| SCHEMBL10618457 | 0.79 | PTAFR (0.82) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258175-B1 | 5-hetero- or aryl-substituted-imidazo[2,1-a]isoquinolines | SANDOZ AG (CH) | 1992-04-01 | — | — | EP | disclosed |
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0357550-A2 | New use of 5-heteroaryl- or 5-aryl-substituted imidazo [2,1-a] isoquinolines | SANDOZ AG (CH) | 1990-03-07 | — | — | EP | disclosed |