Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269669 | 1.00 | MAPT (1.00) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL31077417 | 1.00 | MAPT (1.00) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13073064 | 1.00 | MAPT (1.00) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL5926116 | 1.00 | MAPT (1.00) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3138381 | 0.92 | MAPT (0.85) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| Fumaric Acid SCHEMBL29727810 | 0.89 | MAPT (0.80) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3140285 | 0.89 | MAPT (0.80) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL18622639 | 0.81 | MAPT (0.68) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL3130236 | 0.81 | MAPT (0.68) | MAPTKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13270011 | 0.81 | MAPT (0.68) | MAPTKDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473550-A1 | Indolonaphthyridines | SANDOZ LTD. (CH) | 1992-03-04 | — | — | EP | disclosed |