Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.51 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693995 | 1.00 | PIM1 (0.51) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694001 | 1.00 | PIM1 (0.51) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694388 | 0.93 | PIM1 (0.60) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9692601 | 0.93 | PIM1 (0.60) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9692593 | 0.93 | PIM1 (0.60) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9694558 | 0.89 | PIM1 (0.39) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9693657 | 0.89 | PIM1 (0.39) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9693649 | 0.89 | PIM1 (0.39) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9692559 | 0.88 | PIM1 (0.65) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9692577 | 0.88 | PIM1 (0.65) | PIM1GSK3AGSK3BPIM3CSNK1G1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126337-A | Wide-spectrum bactericides | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0393538-A2 | Thiazetoquinoline-3-Carboxylic acid derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |