Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 5/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083009 | 0.78 | NQO2 (0.47) | KDM4EKMT2AMAPTKCNH2ACHE | |
| SCHEMBL18082993 | 0.78 | NQO2 (0.47) | KDM4EKMT2AMAPTKCNH2ACHE | |
| SCHEMBL8518275 | 0.77 | TLR8 (0.50) | KDM4EKCNH2SMN1; SMN2TLR8L3MBTL1 | |
| SCHEMBL1551894 | 0.77 | KMT2A (0.49) | KDM4EKMT2AMAPTNPC1RAB9A | |
| SCHEMBL1551025 | 0.77 | KMT2A (0.49) | KDM4EKMT2AMAPTNPC1RAB9A | |
| SCHEMBL27905824 | 0.76 | KCNH2 (0.53) | KCNH2SMN1; SMN2TLR8L3MBTL1 | |
| SCHEMBL27863633 | 0.76 | KCNH2 (0.53) | KCNH2SMN1; SMN2TLR8L3MBTL1 | |
| SCHEMBL626394 | 0.76 | KCNH2 (0.53) | KCNH2SMN1; SMN2TLR8L3MBTL1 | |
| SCHEMBL1783878 | 0.75 | ABL1 (0.47) | KCNH2SMN1; SMN2KCNH3ACHE | |
| SCHEMBL18082992 | 0.75 | NQO2 (0.52) | KDM4EKMT2AMAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5115078-A | Self polymerizable phenylquinoxalines, their preparation and use in polyphenylquinoxaline homopolymers and copolymers | THE UNIVERSITY OF AKRON (US) | 1992-05-19 | — | — | US | disclosed |
| US-5030704-A | Self polymerizable phenylquinoxalines, their preparation and use in polyphenylquinoxaline homopolymers and copolymers | THE UNIVERSITY OF AKRON (US) | 1991-07-09 | — | — | US | disclosed |
| WO-1990015836-A1 | SELF-POLYMERIZABLE PHENYLQUINOXALINES | THE UNIVERSITY OF AKRON (US) | 1990-12-27 | — | — | WO | disclosed |