Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.75 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695047 | 1.00 | CHRM2 (0.75) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9022299 | 1.00 | CHRM2 (0.75) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9023113 | 0.86 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9022422 | 0.86 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9022978 | 0.86 | CHRM2 (0.73) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9022840 | 0.86 | CHRM2 (0.73) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9022427 | 0.86 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9693370 | 0.83 | CHRM2 (0.69) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9693487 | 0.83 | CHRM2 (0.69) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9693359 | 0.83 | CHRM2 (0.69) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001142-A | Alzheimer's disease | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5128483-A | CNS Disorders | AMERICAN CYANAMID COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| US-5001142-A | Alzheimer's disease | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0408879-A2 | 1-Substituted-2-(3-amino-1-propynyl)-pyrrolidine derivatives | AMERICAN CYANAMID COMPANY (US) | 1991-01-23 | — | — | EP | disclosed |