Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | DHODH | Q02127 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23725030 | 0.86 | MEN1 (0.64) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL11603474 | 0.84 | MEN1 (0.48) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL11603470 | 0.84 | MEN1 (0.48) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL1023541 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL11605942 | 0.78 | KDM4E (0.44) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL11605945 | 0.78 | KDM4E (0.44) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL12108216 | 0.78 | MAPT (0.64) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL10862774 | 0.78 | MEN1 (0.86) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL11515996 | 0.77 | MEN1 (0.56) | MEN1KMT2AMAPTKDM4EDHODH | |
| SCHEMBL10863268 | 0.77 | DHODH (0.71) | MEN1KMT2AMAPTKDM4EDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007468-A1 | HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-14 | — | — | WO | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |