Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696603 | 1.00 | KMT2A (0.38) | KMT2AHMGCR | |
| SCHEMBL9696231 | 0.85 | HMGCR (0.37) | HMGCR | |
| SCHEMBL9696237 | 0.85 | HMGCR (0.37) | HMGCR | |
| SCHEMBL9697134 | 0.84 | KMT2A (0.39) | KMT2AHMGCR | |
| SCHEMBL9696605 | 0.82 | KMT2A (0.38) | KMT2AHMGCR | |
| SCHEMBL9696601 | 0.82 | KMT2A (0.38) | KMT2AHMGCR | |
| SCHEMBL9696591 | 0.79 | KMT2A (0.38) | KMT2AHMGCR | |
| SCHEMBL9696274 | 0.79 | KMT2A (0.39) | KMT2AHMGCR | |
| SCHEMBL9696283 | 0.79 | KMT2A (0.39) | KMT2AHMGCR | |
| SCHEMBL9697128 | 0.74 | KMT2A (0.39) | KMT2AHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124453-A | Treatment of corresponding aldehyde with lithium bis(tri-methylsilyl)amide | E. R. SQUIBB & SONS, INC. (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0444532-A1 | Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method | E.R. SQUIBB & SONS, INC. (US) | 1991-09-04 | — | — | EP | disclosed |