Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18681489 | 0.84 | GSK3B (0.66) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL9696575 | 0.84 | GSK3B (0.66) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL17275389 | 0.81 | GSK3B (0.61) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL27040064 | 0.81 | GSK3B (0.61) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL17275387 | 0.81 | GSK3B (0.61) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL24808789 | 0.81 | GSK3B (0.61) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL27772799 | 0.79 | GSK3B (0.59) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL14074314 | 0.78 | GSK3B (0.58) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL28755279 | 0.78 | GSK3B (0.58) | GSK3BCES2CES1L3MBTL1LMNA | |
| SCHEMBL28844961 | 0.78 | GSK3B (0.58) | GSK3BCES2CES1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149822-A | PREPARATION OF 2,3-DICHLORO-5-ACETYLPYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |