Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470795 | 0.84 | NPC1 (0.60) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1687867 | 0.81 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2MAPTHDAC3 | |
| SCHEMBL7291713 | 0.81 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2MAPTHDAC3 | |
| SCHEMBL7293746 | 0.81 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2MAPTHDAC3 | |
| SCHEMBL2344788 | 0.80 | KMT2A (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28476713 | 0.78 | NPC1 (0.85) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL30161852 | 0.78 | NPC1 (1.00) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9056724 | 0.77 | TSHR (0.65) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL28568878 | 0.77 | KMT2A (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2344118 | 0.77 | KMT2A (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |