Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696377 | 1.00 | RARB (0.53) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9697304 | 1.00 | RARB (0.53) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9697254 | 1.00 | RARB (0.53) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9696371 | 1.00 | RARB (0.53) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9697266 | 1.00 | RARB (0.53) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9697295 | 1.00 | RARB (0.53) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL10505413 | 0.94 | NPC1 (0.55) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9696305 | 0.91 | RARB (0.56) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9696318 | 0.91 | RARB (0.56) | RARBNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9697449 | 0.91 | RARB (0.56) | RARBNPC1LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141669-A | Liquid crystal compounds having chiral ester head groups | POLAROID CORPORATION (US) | 1992-08-25 | — | — | US | disclosed |