Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 11/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261482 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL28608718 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL5850373 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL7864884 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL1261048 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL24172978 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL177971 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL11497471 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL177765 | 0.94 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL11429610 | 0.91 | CYP3A4 (0.56) | LPAR3LPAR2LPAR1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005788-A1 | NEW PHOSPHONATE DERIVATIVES AS LIPASE AGENTS INHIBITING | NOVO NORDISK A/S (DK) | 1992-04-16 | — | — | WO | disclosed |