Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696785 | 0.93 | KDM4E (0.42) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9699370 | 0.93 | ESR1 (0.44) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9384446 | 0.85 | ESR1 (0.46) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9386632 | 0.85 | ESR1 (0.46) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9382964 | 0.85 | ESR1 (0.46) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9697735 | 0.83 | KDM4E (0.40) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9696813 | 0.82 | KDM4E (0.38) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9194600 | 0.82 | ESR1 (0.49) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9194605 | 0.82 | ESR1 (0.49) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9698230 | 0.81 | ESR1 (0.34) | ESR1CHRM1SLC6A4KCNH2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |