Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751654 | 0.97 | ACE2 (0.41) | ACE2CA1LMNACYP2D6SPHK1 | |
| Ethylene Glycol SCHEMBL9698549 | 0.89 | ACE2 (0.46) | ACE2CA1LMNASPHK1MAPT | |
| SCHEMBL12473668 | 0.86 | ACE2 (0.43) | ACE2CA1LMNACYP2D6SPHK1 | |
| SCHEMBL9577845 | 0.86 | ACE2 (0.43) | ACE2CA1LMNACYP2D6SPHK1 | |
| SCHEMBL1823284 | 0.86 | ACE2 (0.43) | ACE2CA1LMNACYP2D6SPHK1 | |
| SCHEMBL27358203 | 0.86 | ACE2 (0.43) | ACE2CA1LMNACYP2D6SPHK1 | |
| SCHEMBL7749021 | 0.86 | ACE2 (0.43) | ACE2CA1LMNACYP2D6SPHK1 | |
| SCHEMBL1010244 | 0.86 | ACE2 (0.43) | ACE2CA1LMNACYP2D6SPHK1 | |
| SCHEMBL790607 | 0.84 | CA1 (0.50) | ACE2CA1LMNASPHK1MAPT | |
| SCHEMBL5076634 | 0.84 | CA1 (0.50) | ACE2CA1LMNASPHK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488550-A1 | Thermal stabilizers | ROHM AND HAAS COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |