Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CCR6 | P51684 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413768 | 0.97 | CCR6 (0.64) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL413839 | 0.96 | CCR6 (0.62) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL13884597 | 0.95 | CCR6 (0.61) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL415526 | 0.95 | CCR6 (0.60) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL413798 | 0.94 | CCR6 (0.59) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL10025427 | 0.93 | CCR6 (0.58) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL9699451 | 0.88 | CCR6 (0.64) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL10025433 | 0.88 | CCR6 (0.61) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL10025426 | 0.87 | CCR6 (0.60) | HTTCCR6PAX8LMNASMN1; SMN2 | |
| SCHEMBL1919339 | 0.86 | HTT (0.70) | HTTCCR6PAX8LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |