Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 17/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.57 |
| ▸ | CTRC | Q99895 | 3/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699084 | 1.00 | CMA1 (0.67) | CMA1ACEKLK5CTRCF2 | |
| SCHEMBL9699165 | 0.93 | CMA1 (0.65) | CMA1ACECTRCF2PRSS1 | |
| SCHEMBL9699161 | 0.93 | CMA1 (0.65) | CMA1ACECTRCF2PRSS1 | |
| SCHEMBL4452582 | 0.91 | CMA1 (0.65) | CMA1ACEKLK5CTRCF2 | |
| SCHEMBL7354560 | 0.89 | KLK5 (0.59) | CMA1ACEKLK5CTRCF2 | |
| SCHEMBL7354569 | 0.89 | KLK5 (0.59) | CMA1ACEKLK5CTRCF2 | |
| SCHEMBL28067688 | 0.88 | ACE (0.56) | CMA1ACEKLK5 | |
| SCHEMBL28067687 | 0.88 | ACE (0.56) | CMA1ACEKLK5 | |
| SCHEMBL30279308 | 0.86 | F2 (0.60) | CMA1ACEKLK5CTRCF2 | |
| SCHEMBL10297457 | 0.86 | CMA1 (0.62) | CMA1ACEKLK5CTRCF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004370-A1 | MODIFIED DI- AND TRIPEPTIDYL IMMUNOSUPPRESSIVE COMPOUNDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1992-03-19 | — | — | WO | claimed |