Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748293 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL4748690 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL31498425 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL4749149 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL7210942 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL4745433 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL3731301 | 0.98 | NR5A1 (0.49) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL9850682 | 0.97 | NR5A1 (0.49) | NR5A1TSHRTHRAMAPTCA12 | |
| SCHEMBL1608519 | 0.95 | CA12 (0.50) | MAPTCA12CA1CA2CA3 | |
| SCHEMBL30334792 | 0.95 | CA12 (0.50) | MAPTCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518636-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |
| EP-0517498-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| EP-0199152-A2 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4605669-A | Lipoxygenase inhibiting naphthohydroxamic acids | ABBOTT LABORATORIES (US) | 1986-08-12 | — | — | US | disclosed |