Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590368 | 0.98 | ATM (0.65) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL4865397 | 0.98 | ATM (0.71) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL11408812 | 0.96 | ATM (0.68) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL10590320 | 0.96 | ATM (0.68) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL20985659 | 0.96 | ATM (0.74) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL20985652 | 0.94 | ATM (0.77) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL6927269 | 0.89 | MEN1 (0.70) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL28366947 | 0.89 | ATM (0.85) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL10722542 | 0.89 | ATM (0.85) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL27487132 | 0.89 | ATM (0.85) | ATMKMT2AMEN1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |