Sugi Predict

Sugi Predict / Compounds / SCHEMBL9699233

SCHEMBL9699233

SCHEMBL9699233

C[C@]1(CO)CO[C@@H](c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SOAT1 P35610 14/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737543 1.00 SOAT1 (0.75) SOAT1
SCHEMBL9698135 1.00 SOAT1 (0.75) SOAT1
Hydrochloric Acid SCHEMBL9737544 0.99 SOAT1 (0.73) SOAT1
Hydrochloric Acid SCHEMBL9737229 0.99 SOAT1 (0.73) SOAT1
Hydrochloric Acid SCHEMBL9737227 0.99 SOAT1 (0.73) SOAT1
SCHEMBL9740337 0.90 SOAT1 (0.77) SOAT1
SCHEMBL9738395 0.88 SOAT1 (0.86) SOAT1
SCHEMBL7075191 0.86 SOAT1 (1.00) SOAT1
SCHEMBL9737115 0.86 SOAT1 (0.72) SOAT1
SCHEMBL9737710 0.86 SOAT1 (0.72) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102900-A Antilipemic and anticholesterol agents RHONE-POULENC RORER S.A. (FR) 1992-04-07 — — US claimed
WO-1992017470-A1 IMIDAZOLES RHONE-POULENC RORER LIMITED (GB) 1992-10-15 — — WO disclosed
EP-0506437-A1 Imidazoles RHONE POULENC RORER LIMITED (GB) 1992-09-30 — — EP disclosed
US-5102900-A Antilipemic and anticholesterol agents RHONE-POULENC RORER S.A. (FR) 1992-04-07 — — US disclosed
EP-0424195-A1 Imidazoles RHONE-POULENC SANTE (FR) 1991-04-24 — — EP disclosed