Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.78 |
| ▸ | CNR2 | P34972 | 6/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | MTOR | P42345 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | RGS12 | O14924 | 1/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700473 | 0.88 | CNR1 (0.78) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9700346 | 0.88 | CNR1 (1.00) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL3458112 | 0.88 | CNR1 (1.00) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9701415 | 0.87 | CNR1 (0.77) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9701686 | 0.87 | CNR1 (0.88) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9699308 | 0.85 | CNR1 (0.85) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9701596 | 0.85 | CNR1 (0.73) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9700366 | 0.85 | CNR1 (0.76) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9701402 | 0.84 | CNR1 (0.75) | CNR1CNR2CYP3A4CYP2C9MEN1 | |
| SCHEMBL9700496 | 0.84 | CNR1 (0.83) | CNR1CNR2CYP3A4CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112820-A | Vision defects | STERLING DRUG INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5109135-A | 2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates | STERLING DRUG INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5066803-A | Chemical intermediates for analgesics | STERLING DRUG INC. (US) | 1991-11-19 | — | — | US | disclosed |