Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064879 | 0.81 | SRC (0.45) | SRCNR1H2MEN1KMT2AL3MBTL1 | |
| SCHEMBL19943156 | 0.81 | NR1H2 (0.40) | SRCNR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL8145885 | 0.80 | NR1H2 (0.38) | SRCNR1H2MEN1KMT2AL3MBTL1 | |
| SCHEMBL25557523 | 0.79 | NR1H2 (0.40) | SRCNR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL16376318 | 0.78 | NR1H2 (0.42) | NR1H2MEN1KMT2ACYP1A2POLB | |
| SCHEMBL28491555 | 0.77 | NR1H2 (0.36) | SRCNR1H2MEN1KMT2AL3MBTL1 | |
| SCHEMBL28502069 | 0.77 | NR1H2 (0.36) | SRCNR1H2MEN1KMT2AL3MBTL1 | |
| SCHEMBL30543805 | 0.77 | BRD4 (0.40) | SRCNR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL30543797 | 0.77 | NR1H2 (0.46) | SRCNR1H2MEN1KMT2ACYP1A2 | |
| SCHEMBL25957274 | 0.77 | NR1H2 (0.46) | SRCNR1H2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |