Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699479 | 1.00 | CYP19A1 (0.76) | CYP19A1ALDH1A1HPGDESR1ESR2 | |
| SCHEMBL10580905 | 0.95 | CYP19A1 (0.76) | CYP19A1ALDH1A1HPGDESR1ESR2 | |
| SCHEMBL2351752 | 0.94 | CYP19A1 (0.65) | CYP19A1HPGD | |
| SCHEMBL2351745 | 0.94 | CYP19A1 (0.65) | CYP19A1HPGD | |
| SCHEMBL2351748 | 0.94 | CYP19A1 (0.65) | CYP19A1HPGD | |
| SCHEMBL2355442 | 0.88 | CYP19A1 (0.58) | CYP19A1HPGD | |
| SCHEMBL2355438 | 0.88 | CYP19A1 (0.58) | CYP19A1HPGD | |
| SCHEMBL2355437 | 0.88 | CYP19A1 (0.58) | CYP19A1HPGD | |
| SCHEMBL2353207 | 0.85 | CYP19A1 (0.55) | CYP19A1ALDH1A1HPGD | |
| SCHEMBL2353212 | 0.85 | CYP19A1 (0.55) | CYP19A1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479570-A2 | Animal growth promotion with aromatase inhibitors | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |