SCHEMBL9700085

SCHEMBL9700085

Nc1cc(O)cc(O)c1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.57
ACHE P22303 2/20 0.57
PTPN1 P18031 2/20 0.48
PTPN11 Q06124 2/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
HPGD P15428 2/20 0.48
FASN P49327 1/20 0.46
PTGS1 P23219 1/20 0.43
DRD3 P35462 1/20 0.43
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA7 P43166 4/20 0.41
CA9 Q16790 4/20 0.41
CA14 Q9ULX7 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15440294 0.84 CA12 (0.43) CYP3A4ACHEPTPN1MEN1KMT2A
SCHEMBL5603948 0.83 CYP3A4 (0.70) CYP3A4ACHEPTPN1PTPN11MEN1
SCHEMBL180437 0.83 CYP3A4 (0.70) CYP3A4ACHEPTPN1PTPN11MEN1
SCHEMBL22939025 0.80 CDC25B (0.49) CYP3A4ACHEMEN1KMT2AHPGD
SCHEMBL8215504 0.80 CYP3A4 (0.67) CYP3A4ACHEPTPN1PTPN11MEN1
Benzene SCHEMBL28591583 0.80 CYP3A4 (0.67) CYP3A4ACHEPTPN1PTPN11MEN1
Water SCHEMBL1285656 0.80 CYP3A4 (0.67) CYP3A4ACHEPTPN1PTPN11MEN1
SCHEMBL8206510 0.80 CYP3A4 (0.67) CYP3A4ACHEPTPN1PTPN11MEN1
Methane SCHEMBL28043126 0.80 CYP3A4 (0.67) CYP3A4ACHEPTPN1PTPN11MEN1
SCHEMBL2127547 0.79 CYP3A4 (0.59) CYP3A4ACHEPTPN1PTPN11MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631865-A Preparation method of avenanthramide and derivative thereof 南京华狮新材料有限公司 2017-05-10 CN disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed