SCHEMBL9700109

SCHEMBL9700109

CCC(CN1CCN(c2ccccc2)CC1)C1(C)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 14/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700139 0.91 SOAT1 (0.65) SOAT1
SCHEMBL9697937 0.82 SOAT1 (0.58) SOAT1
SCHEMBL9700107 0.81 SOAT1 (0.64) SOAT1
SCHEMBL9698723 0.81 SOAT1 (0.57) SOAT1
SCHEMBL9698761 0.81 SOAT1 (0.61) SOAT1
SCHEMBL9700096 0.79 SOAT1 (1.00) SOAT1
SCHEMBL9698130 0.78 SOAT1 (0.41) SOAT1
SCHEMBL9700138 0.76 SOAT1 (0.65) SOAT1
SCHEMBL9700111 0.74 SOAT1 (0.71) SOAT1
SCHEMBL7075191 0.73 SOAT1 (1.00) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992017470-A1 IMIDAZOLES RHONE-POULENC RORER LIMITED (GB) 1992-10-15 WO disclosed
EP-0506437-A1 Imidazoles RHONE POULENC RORER LIMITED (GB) 1992-09-30 EP disclosed