Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 2/20 | 0.39 |
| ▸ | KDM6A | O15550 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694192 | 0.82 | KDM4E (0.50) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| SCHEMBL15457888 | 0.79 | KDM4E (0.40) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| SCHEMBL15453008 | 0.79 | KDM4E (0.40) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| SCHEMBL15453035 | 0.78 | KDM4E (0.39) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| Hydrochloric Acid SCHEMBL15453015 | 0.78 | KDM4E (0.39) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| SCHEMBL15453048 | 0.78 | KDM4E (0.39) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| Hydrochloric Acid SCHEMBL15453039 | 0.77 | KDM4E (0.38) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| Hydrochloric Acid SCHEMBL15453040 | 0.77 | KDM4E (0.38) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| Hydrochloric Acid SCHEMBL15453043 | 0.76 | KDM4E (0.40) | KDM4EDOHHKDM6AKDM4ACYP2C9 | |
| SCHEMBL15457911 | 0.75 | KDM4E (0.36) | KDM4EDOHHKDM6AKDM4ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012131-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494754-A1 | 3-hydroxypyridin-4-one derivatives as pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-07-15 | — | — | EP | disclosed |