Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700242 | 0.86 | TBXA2R (0.62) | TBXA2RPPARACCR9LMNA | |
| SCHEMBL9682366 | 0.84 | TBXA2R (0.50) | ALDH1A1NPSR1TBXA2RHSD17B10GAA | |
| SCHEMBL9700304 | 0.79 | KDM4E (0.39) | ALDH1A1NPSR1TBXA2RHSD17B10GAA | |
| SCHEMBL9700250 | 0.72 | CCR9 (0.41) | TBXA2RCCR9LMNA | |
| SCHEMBL28565179 | 0.71 | TBXA2R (0.53) | ALDH1A1NPSR1TBXA2RTSHRPOLB | |
| SCHEMBL3103170 | 0.69 | TBXA2R (0.48) | ALDH1A1NPSR1TBXA2RHSD17B10HPGD | |
| SCHEMBL469433 | 0.69 | CYP1A2 (0.56) | ALDH1A1NPSR1GAATSHRPOLB | |
| SCHEMBL9273498 | 0.69 | TBXA2R (0.66) | NPSR1TBXA2RHSD17B10HPGDTSHR | |
| SCHEMBL9700200 | 0.68 | TBXA2R (0.56) | ALDH1A1TBXA2RATM | |
| SCHEMBL9682372 | 0.67 | KDM4E (0.39) | ALDH1A1NPSR1TBXA2RTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |