Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 3/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666637 | 0.80 | KDM4E (0.45) | SLC6A4SLC6A2CYP1A2KDM4EMEN1 | |
| SCHEMBL15074810 | 0.79 | MCHR1 (0.37) | MCHR1SLC6A4SLC6A2CYP1A2KDM4E | |
| SCHEMBL27920845 | 0.78 | MCHR1 (0.56) | MCHR1SLC6A4SLC6A2CYP1A2KDM4E | |
| SCHEMBL18729400 | 0.78 | MRGPRX4 (0.38) | MCHR1SLC6A4SLC6A2CYP1A2MEN1 | |
| SCHEMBL18729401 | 0.78 | MRGPRX4 (0.38) | MCHR1SLC6A4SLC6A2CYP1A2MEN1 | |
| SCHEMBL3616269 | 0.77 | CYP1A2 (0.56) | SLC6A4SLC6A2CYP1A2KDM4EMEN1 | |
| SCHEMBL11499494 | 0.76 | HTR1B (0.47) | SLC6A4SLC6A2CYP1A2KDM4EMEN1 | |
| SCHEMBL23958047 | 0.75 | SLC6A4 (0.50) | SLC6A4SLC6A2CYP1A2KDM4EMEN1 | |
| SCHEMBL12936076 | 0.74 | SCN4A (0.47) | SLC6A4CYP1A2KDM4ECYP2D6HTR2B | |
| SCHEMBL17014662 | 0.74 | SLC6A2 (0.45) | MCHR1SLC6A4SLC6A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104959-A | POLYURETHANE-BASED REACTIVE ADHESIVES IN WHICH THE ISOCYANATE IS STABILIZED BY A POLYETHER AMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |