Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699782 | 0.83 | FGFR1 (0.47) | CYP11B2CYP11B1PDE3BPDE3A | |
| SCHEMBL9724606 | 0.75 | CYP11B1 (0.45) | CYP11B2CYP11B1ALDH1A1CRBNPDE3B | |
| SCHEMBL9699737 | 0.74 | PSEN1 (0.44) | CYP11B2CYP11B1CRBNPDE3BPDE3A | |
| SCHEMBL9700875 | 0.73 | CYP11B1 (0.43) | CYP11B2CYP11B1ALDH1A1LMNACRBN | |
| SCHEMBL9700782 | 0.70 | PDE3B (0.46) | CYP11B2CYP11B1ALDH1A1LMNACRBN | |
| SCHEMBL9700740 | 0.68 | PDE3B (0.64) | CYP11B2CYP11B1LMNACRBNPDE3B | |
| SCHEMBL434348 | 0.68 | CYP11B1 (0.51) | CYP11B2CYP11B1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL17947703 | 0.66 | CYP17A1 (0.44) | CYP17A1 | |
| SCHEMBL17691571 | 0.66 | HTT (0.56) | ALDH1A1CYP17A1 | |
| SCHEMBL24427833 | 0.65 | CYP11B1 (0.55) | CYP11B2CYP11B1CRBNPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171851-A | Cardiac stimulant | DONG-A PHARM. CO., LTD. (KR) | 1992-12-15 | — | — | US | claimed |
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | claimed |
| US-5171851-A | Cardiac stimulant | DONG-A PHARM. CO., LTD. (KR) | 1992-12-15 | — | — | US | disclosed |
| EP-0510235-A1 | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same | DONG-A PHARM. CO., LTD. (KR) | 1992-10-28 | — | — | EP | disclosed |