Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19890539 | 0.81 | CCR8 (0.55) | CCR8KMT2ACYP19A1NQO2KDM4E | |
| SCHEMBL30940174 | 0.81 | CCR8 (0.55) | CCR8KMT2ACYP19A1NQO2KDM4E | |
| SCHEMBL7283419 | 0.81 | CCR8 (0.55) | CCR8KMT2AKDM4EALDH1A1HDAC4 | |
| SCHEMBL7291038 | 0.81 | CYP19A1 (0.50) | CCR8KMT2ACYP19A1NQO2KDM4E | |
| SCHEMBL4374264 | 0.81 | CCR8 (0.44) | CCR8KMT2A | |
| SCHEMBL29052296 | 0.77 | KDM4E (0.57) | CCR8KMT2ANQO2KDM4EALDH1A1 | |
| SCHEMBL10158695 | 0.77 | CCR8 (0.47) | CCR8KMT2ACYP19A1NQO2KDM4E | |
| SCHEMBL19318056 | 0.74 | CCR8 (1.00) | CCR8KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30774416 | 0.74 | CCR8 (1.00) | CCR8KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7835424 | 0.74 | BRD4 (0.45) | KMT2ACYP19A1NQO2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |