Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21960161 | 0.86 | CYP11B1 (0.73) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5702666 | 0.84 | CYP1A1 (0.74) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15296276 | 0.83 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL968951 | 0.81 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21044298 | 0.81 | MKNK1 (0.64) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12302844 | 0.81 | CYP11B1 (0.65) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1623766 | 0.79 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12919969 | 0.79 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL486081 | 0.79 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1569892 | 0.78 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |