Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.75 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701545 | 1.00 | TBXA2R (0.75) | TBXA2RALOX5APAGTR1AGTR2ALDH1A1 | |
| SCHEMBL9681427 | 0.94 | TBXA2R (0.76) | TBXA2RALOX5AP | |
| SCHEMBL9681431 | 0.94 | TBXA2R (0.76) | TBXA2RALOX5AP | |
| SCHEMBL9681438 | 0.94 | TBXA2R (0.76) | TBXA2RALOX5AP | |
| SCHEMBL9682913 | 0.89 | TBXA2R (0.76) | TBXA2RALOX5APAGTR1AGTR2 | |
| SCHEMBL9682925 | 0.89 | TBXA2R (0.76) | TBXA2RALOX5APAGTR1AGTR2 | |
| SCHEMBL9682918 | 0.89 | TBXA2R (0.76) | TBXA2RALOX5APAGTR1AGTR2 | |
| SCHEMBL9699150 | 0.86 | TBXA2R (1.00) | TBXA2RALOX5AP | |
| SCHEMBL9682427 | 0.86 | TBXA2R (1.00) | TBXA2RALOX5AP | |
| SCHEMBL9683587 | 0.81 | TBXA2R (1.00) | TBXA2RALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5021443-A | Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present | LABORATOIRES UPSA (FR) | 1991-06-04 | — | — | US | disclosed |